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Medicine, Its Use And Remidies for Ailments - Actilyse
Actilyse (Ak-til-eyes) is a medicine which is used in ischaemic stroke, pulmonary embolism and treatment of myocardial infarction. (Blood clotting, Heart attack and Stroke) Actilyse contains alteplase.
Medicines are used to treat, control or prevent a condition. Some medicines will give you immediate relief from your symptoms while others take much longer to work.
Actilyse is an injection that is usually given by a healthcare professional. The person responsible for giving you your medicine will make sure that you get the right dose. If you feel that the medicine is making you feel unwell or you think it is not working, you should talk to someone who is involved in your care.
Actilyse can be used to break up a blood clot which has blocked a blood vessel. This may help blood flow through the blood vessel to return to normal. Actilyse needs to be given as soon as possible after the blockage has occurred to have the most benefit.
How to take your medicine
This medicine will be given to you as an injection. If you have any concerns about this medicine or how this will be given to you, talk to someone who is involved in your medical care.
Is this medicine suitable for you
Actilyse is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.
Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:
- are bleeding
- are elderly
- are prone to bleeding
- have a tumour
- have certain heart or circulation problems
- have damage to the brain, nerves or spinal cord
- have gastrointestinal problems
- have had a gastrointestinal ulcer within the past three months
- have had a stroke
- have had an injury or an operation within the past three months
- have had certain medical procedures such as a biopsy or an injection into a muscle
- have had to be resuscitated within the past ten days
- have liver problems
- have or have had cerebrovascular problems
- have pancreatitis
- have recently given birth to a baby
- have recently had bleeding problems
Furthermore, the prescriber may not prescribe this medicine for a child.
Over time it is possible that Actilyse can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Actilyse has become unsuitable, it is important that the prescriber is contacted immediately.
Side Effects
Some side-effects may be serious while others may only be a mild inconvenience. Very occasionally, certain side-effects can be beneficial.
Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.
Very common: More than 10% of people who take Actilyse
- bleeding - certain types of bleeding may lead to the need for a blood transfusion. Some types of bleeding may result in permanent disability or may be fatal
- lowered blood pressure
Common: Between 1% and 10% of people who take Actilyse
- bruising
- high temperature
- nausea
- nose bleed
- vomiting
Uncommon: Between 0.1% and 1% of people who take Actilyse
- anaphylactic reactions such as skin rashes, urticaria, bronchospasm, angioedema, lowered blood pressure or shock - some of these may be life threatening. If you get any type of anaphylactic reaction you must immediately inform a member of the medical team who is involved in your care
- bleeding of the gums
- embolus
Isolated reports
- central nervous system problems such as convulsions
The frequency of these side effects is unknown
- bleeding in the eye
- heart problems or pulmonary embolism - some of these may be life-threatening
If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away.
Taking other medicines
If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.
The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.
Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.
The following medicines may interact with Actilyse:
- heparin
- warfarin
The following types of medicine may interact with Actilyse:
- ACE inhibitors
- coumarin derivatives
- low molecular weight heparins
- medicines that may increase the chances of bleeding
- oral anticoagulants
- platelet aggregation inhibitors
If you are taking Actilyse and one of the above medicines or types of medicines, make sure your prescriber knows about it.
Complementary preparations and vitamins
Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.
Make sure you tell your prescriber the names of all the complementary preparations and vitamins that you are taking or are planning to take.
Your prescriber can then advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins will have on your condition.
- there are no known interactions between Actilyse and any complementary preparations or vitamins
If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell your prescriber.
Driving and operating machinery
When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.
- considerations about how this medicine affects driving or operate machinery do not apply to Actilyse
Diet
Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.
- there are no specific foods that you must exclude from your diet when having Actilyse
Alcohol
Alcohol can interact with certain medicines.
- there are no known interactions between alcohol and Actilyse
Family planning and pregnancy
Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.
Careful consideration needs to be given to the risks and the benefits of using this medicine during pregnancy.
You need to discuss your specific circumstances with your doctor to make a decision about whether you are going to take this medicine during pregnancy. You should only take this medicine during pregnancy if your doctor thinks you need to take it. If the decision is that you should not have Actilyse, then you should discuss whether there is an alternative medicine that you could take during pregnancy.
Breast Feeding
Certain medicines can pass into breast milk and may reach your baby through breast-feeding.
- it is not known whether this medicine passes into breast milk
Ingredients
Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. Some may be used to prolong the life of the medicine.
Actilyse contains:
- alteplase
- L-arginine
- phosphoric acid
- polysorbate 80
- water for injections
Disclaimer - eHealth Treats does not endorse or recommend any commercial products, processes, or services. Consulting a Qualified Medical Practitioner is always recommended. eHealth Treats does not and should not be taken as a substitute for a Qualified Medical Practitioner.
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