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Precautions against Avian influenza

Avian influenza A (H5N1) or "bird flu" is a serious viral infection that occurs primarily in poultry, migratory waterfowl, and-less commonly-pigs. Although it is unusual for humans to acquire influenza virus infections from birds, human infections and deaths caused by the H5N1 virus have occurred. Humans have no immunity to this virus, and a human avian flu vaccine is not yet available, although vaccine trials are underway. Once a "bird flu" vaccine becomes available, 2 doses will be needed, given 1 month apart.

Where Are People At Risk for Avian Influenza?

Anywhere there are cases of H5N1 avian influenza occurring in birds, there is a risk that humans can also become ill if exposed to this virus. During 2005 and/or 2006, H5N1 outbreaks or occurrences among poultry and/or other birds have been reported in the following countries: Afghanistan, Albania, Austria, Azerbaijan, Bosnia and Herzegovina, Burkina Faso, Bulgaria, Burma (Myanmar), Cambodia, Cameroon, China, Cote d'Ivoire, Croatia, Czech Republic, Denmark, Djibouti, Egypt, France, Germany, Georgia, Greece, Hong Kong, Hungary, India, Indonesia, Iran, Iraq, Israel, Italy, Jordan, Kazakhstan, Laos, Malaysia, Mongolia, Niger, Nigeria, Pakistan, Poland, Romania, Russia, Serbia and Montenegro, Slovakia, Slovenia, Spain, Sudan, Sweden (H5), Switzerland, Thailand, Turkey, Ukraine, United Kingdom, and Viet Nam.

Human cases and deaths have occurred in Thailand, Viet Nam, Indonesia, Cambodia, China, Turkey, Iraq, Azerbaijan, Egypt, and Djibouti. For a current list of affected countries, see: www.oie.int/downld/avian influenza/a_ai-asia.htm and www.wpro.who.int/health_topics/avian_influenza/. For cumulative human cases by country, see: www.who.int/csr/disease/avian_influenza/country/en/.

How do People Get Infected?

The H5N1 virus is spread by domestic ducks, poultry, and wild migratory birds. Most human cases are thought to have resulted from direct contact with sick or infected poultry (e.g., in live animal markets or poultry farms) or with their droppings, respiratory secretions, or eye secretions, or through contact with contaminated surfaces. It is possible that humans can be exposed by eating undercooked, infected poultry or eggs or duck blood. Theoretically, the virus may also be transmitted through inhalation of dried, airborne poultry feces. Human-to-human transmission is extremely rare.

The current H5N1 virus, which is adapted to birds, may have an incubation period of 1 week, but if it is able to adapt to humans and becomes a pandemic strain, the incubation period is likely to be 2 days (similar to seasonal influenza).

What are the symptoms of Avian Influenza?

Initially avian (H5N1) influenza may appear like a severe case of regular, seasonal influenza with typical flu-like symptoms (fever, chills, cough, runny nose, sore throat, muscle aches, headaches), but the person then deteriorates rapidly, suddenly developing severe pneumonia and respiratory distress about 3-5 days into the illness. Other symptoms might include eye inflammation, severe diarrhea, encephalitis (brain inflammation), seizures, or coma.

How to Prevent Avian Influenza?

If you plan to travel to an area where H5N1 avian influenza has been detected in domestic poultry or humans, take the following precautions:

In some situations, your medical provider may ask you to include an anti viral drug called oseltamivir (Tamiflu) in your medical kit. If oseltamivir is unavailable, zanamivir (Relenza) is another option, but it is in extremely short supply and may not generally be available.

Can H5N1 Infection Be treated?

As noted above, oseltamivir (Tamiflu) or zanamivir (Relenza) are the only available therapy for treatment of avian influenza. Ask your health care provider if you should carry one of these drugs with you and how and when to use it.

What to do whey You fall Sick?

If you become sick with a fever or any flu-like symptoms during travel or for 10 days after travel to an H5N1-infected area, (i.e., where cases are occurring in domestic poultry or humans), seek medical care. Inform your physician of your symptoms and travel itinerary, including possible exposure.

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